AMPA - Wikipedia
WEBα-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, better known as AMPA, is a compound that is a specific agonist for the AMPA receptor, where it mimics the effects of the neurotransmitter glutamate.
AMPA receptor - Wikipedia
WEBAMPA receptor. The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane receptor for glutamate ( iGluR) and predominantly Na + ion channel that mediates fast synaptic transmission in the central nervous system (CNS).
AMPA Receptor - an overview | ScienceDirect Topics
WEBAMPA receptors mediate fast excitatory synaptic transmission in the central nervous system. These receptors play a key role in synaptic plasticity being involved in long-term potentiation (LTP) and long-term depression (LTD) of …
Visualization of AMPA receptors in living human brain with ... - Nature
WEBJan 20, 2020 · A newly developed PET tracer allows visualization of AMPA receptors in the living human brain, providing a new tool to study their potential involvement in neurological or psychiatric disorders.
Presynaptic AMPA Receptors in Health and Disease - PMC
WEBAug 31, 2021 · AMPA receptors (AMPARs) are ionotropic glutamate receptors that play a major role in excitatory neurotransmission. AMPARs are located at both presynaptic and postsynaptic plasma membranes. A huge number of studies investigated the role of postsynaptic AMPARs in the normal and abnormal functioning of the mammalian central …
Assembly of AMPA receptors: mechanisms and regulation
WEBJan 1, 2015 · AMPA receptors (AMPARs) play a critical role in excitatory glutamatergic neurotransmission. The number and subunit composition of AMPARs at synapses determines the dynamics of fast glutamatergic signalling. Functional AMPARs on the cell surface are tetramers.
Regulatory mechanisms of AMPA receptors in synaptic plasticity
WEBFeb 1, 2007 · AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid)-type glutamate receptors (AMPARs) are the main transducers of rapid excitatory transmission in the mammalian CNS, and recent...
AMPA - an overview | ScienceDirect Topics
WEBα-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors (AMPARs) mediate fast synaptic transmission at excitatory synapses in the central nervous system. Proper AMPAR function and regulation are critical to neuronal development, synaptic plasticity, and structural remodeling.
Synaptic AMPA receptor composition in development, plasticity …
WEBApr 15, 2016 · In this Review, Henley and Wilkinson provide an overview of how different receptor subunits affect AMPAR assembly, trafficking and function under normal and pathological conditions. AMPA...
AMPA - an overview | ScienceDirect Topics
WEBAbstract. α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid ( AMPA )-type glutamate receptors (AMPARs) mediate the majority of fast excitatory synaptic transmission in the brain. AMPARs dynamically cycle in and out of the postsynaptic membrane in an activity-dependent manner.
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